iui o?iie?aneei aieaaui neia?iiii (OAN). I?e yoii, eae
i?aaeei, ni?aoa?ony ?acee?iua oeiu aiee: niiaoe?aneay, aenoa-
?aeuiay, iae?iiaoe?aneay. O?iie?aneee aieaaie neia?ii iao-
neiaeai ii?a?aieai einoae neaeaoa, eiii?annae ia?aia, ei-
oeeuo?aoae iyaeeo oeaiae, aioo?aiieo i?aaiia, eo?aauie ii-
a?a?aaieyie. Iiyoiio aeooaeuiie i?iaeaiie i?e ?aea auea e
inoaaony i?iaeaia ai?uau n aieu?. Iiieii o?aaeoeiiiiai
iaacaieeaaiey, ?aeiiaiaiaaiiiai AIC, a oae?a aeuoa?iaoeaiie
noaiu oa?aiee OAN, ?ac?aaioaiiie IIEIE ei. I.A Aa?oaia, a
Iao?icaaianeii iieieiae?aneii aeniaina?a auee i?eiaiaiu
oeaieiiaua aeieaau, eae a ?enoii aeaa, oae e a ni?aoaiee n a?o-
aeie iaoiaaie iaacaieeaaiey. Anaai a 1993-96 aa. auiieiaiu
305 oeaieiiauo aeieaa o eieo?aaaeuiuo aieuiuo. Ec ieo io?-
?ei 204, ?aiuei 101 a aic?anoa io 21 ai 81 aiaa. A noaoeiia?-
iuo oneiaeyo iieo?eee oa?aie? 64 aieuiuo, a iieeeeeieea — 65,
ia aiio — 166. Ia?ae?iay iiooieu eiaea neaao?uea eieaeeca-
oee: eaaeea — 51, iiei?iay ?aeaca — 55, ?aeoaie — 48, i?yiay
eeoea — 42, i?aanoaoaeuiay ?aeaca — 14, ii?aaie iocu?u —
10, iaoea e ye?ieee -12, i?i?ea eieaeecaoee-73. Oeaieiiaua
aeieaau i?eiaiyee i?e oia?aiiii e neeuiii aieaaii neia?i-
ia (2-3 aaeea ii 5-aaeuiie oeaea aa?aaeuiuo ioaiie) ia oiia
i?aaoanoaiaaaoae iaeiyooaeoeaiie eee iayooaeoeaiie oa?-
iaeioa?aiee, ?oi iauyniyaony ionoonoaeai nia?aiaiiuo yooa-
eoeaiuo oa?iaeii?aia?aoia.
Oi?ioee aiaeuaaoe?aneee yooaeo aue ioia?ai o 245 aieuiuo
n aieu? neaaie e n?aaiae eioaineaiinoe (2-3 aaeea ii 5-aaeeu-
iie oeaea aa?aaeuiuo ioaiie). O yoeo aieuiuo iinea i?iaaaai-
iiai ea?aiey oiaiuoeeanu iio?aaiinou ai aaaaaiee aiaeuaaoe-
eia, ?oi iicaieeei nieceou, a eiiaaa e iieiinou? ioiaieou (oioy
au a?aiaiii) iaaeeaiaioicio? iaa?oceo. Iiauneeinu ea?anoai
?ecie, oaaee?eeanu i?iaie?eoaeuiinou ii?iiai nia, iiaune-
eanu oece?aneay aeoeaiinou, oeo?oeeenu aiiaoeo e naii?oano-
aea.
Niiieoaeuiue yooaeo aue ioia?ai o 52 aieuiuo, ionoonoaea
yooaeoa — o 38 aieuiuo. Yoi auee aieuiua n naiie neeuiie ai-
eu? (4 aaeea ii 5-aaeuiie oeaea aa?aaeuiuo ioaiie). Iiyoiio
o oaeeo aieuiuo i?eiaiyeenu aiiieieoaeuii ?acee?iua aeau
?aaeiia?iiai e i?iaiaieeiaiai iaacaieeaaiey. O aieuiuo n ii-
ei?eoaeuiui yooaeoii i?e aiciaiiaeaiee eee oneeaiee aiea-
aiai neia?iia (102 aieuiuo) i?iaiaeee iiaoi?iua eo?nu oea-
ieiiauo aeieaa.
Iaeeo?oee yooaeo iaie ioia?ai o aieuiuo n ia?ae?iie ei-
eaeecaoeae iiooiee a iiei?iie ?aeaca, ?aeoaea,
i?aanoaoaeuiie ?aeaca.
I?e i?iaaaaiee oeaieiiauo aeieaa ioia?aiu neaao?uea
iiai?iua yooaeou:
— aeea?ae?aneea ?aaeoee a aeaa e?aieaieou — 6 aieuiuo;
— oia?aiiay aeiioiiey-56 aieuiuo (eoie?iaaia no?oeiui
aaaaaieai iieeae?eeia);
— a?aaeea?aey — 3 aieuiuo (ono?aiaia ao?iieiii).
Oaeei ia?acii, oeaieiiaua aeieaau ii?ii ?aeiiaiaiaaou
i?e ea?aiee o?iie?aneiai aieaaiai neia?iia o iieieiae?aneeo
aieuiuo aaeao yooaeoeaiinoe, ainooiiinoe, yeiiiie?iinoe e
aaciianiinoe yoiai iaoiaa, o?eouaay ?anoia ionoonoaea yooae-
oeaiuo oa?iaeii?aia?aoia.
Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey, 1997, ¹ 5, no?. 29.
ÈÌÌÓÍÎÊÎÐÐÅÊÖÈß ÏÐÈ
ÐÀÑÏÐÎÑÒÐÀÍÅÍÍÛÕ ÔÎÐÌÀÕ
ÇËÎÊÀ×ÅÑÒÂÅÍÍÛÕ ÍÎÂÎÎÁÐÀÇÎÂÀÍÈÉ
A.I. Eociaoia, E.E. Ei?iaeiaa, A.E. Aaeyaa,
A.N. ?anneac?eeiaa, A.A. Aaaayio, E.C. Aaeuoa?
IEEYI ii. I.O. Aaiaeae
Eaoaa?a iieieiaee IINE ei. I.A. Naiaoei, Iineaa
Eiioiiei??aeoey yaeyaony iaiei ec yooaeoeaiuo n?aanoa
i?ioeeaeoeee iaoanoace?iaaiey i?e iia?aaaeuiuo oi?iao ii-
aiia?aciaaiee (3,5). I?e ?ani?ino?aiaiiuo oi?iao ceiea?ano-
aaiiuo iiaiia?aciaaiee ia?aa eiioiiei??aeoeae noaayony
eiua caaa?e: noaaeeecaoey eee ia?aoiia ?acaeoea iiooieaaiai
i?ioanna n aiaaaaieai aieuiiai ai iia?aaaeuiiai ninoiyiey
eee aicii?iinoe i?eiaiyou iieeoeieioa?aie? (IOO), a oae?a
iiauoaiea ea?anoaa ?ecie a oa?ieiaeuiie noaaee. Eeeie?aneee
iiuo iieacuaaao, ?oi aey iaeioi?uo eaoaai?ee aieuiuo ia?aay e
iaeaieaa o?oaiay caaa?a aiieia ainoe?eia i?e eniieuciaaiee
eiioiiei??eae?o?uae oa?aiee. Oeo?oaiey ea?anoaa ?ecie oaa-
aony aiaeouny i?aeoe?anee ai anao neo?ayo.
A ianoiyuai niiauaiee i?eaiayony ?acoeuoaou eiiaeie?i-
aaiiiai ea?aiey (o.a. i?e ni?aoaiee oe?o?ae?aneeo e oeoinoaoe-
?aneeo iaoiaia n eiioiiei??eae?o?ueie i?aia?aoaie) aieu-
iuo ?aeii iiei?iie ?aeacu (?I?), ye?ieeia (??) e a?oaeo ei-
eaeecaoee.
A ea?anoaa eiioiiei??eae?o?ueo n?aanoa i?eiaiyeny i?a-
ia?ao eaeeeioa?ii (EO), ?ac?aaioaiiue a iaoae eaai?aoi?ee e
?aeiaa?aneee eaeeioeoa?iue eioa?oa?ii (?EE) n aeoeaiinou? 1
iei. ME. Iaa i?aia?aoa neioace?o?ony a eoeuoo?a aiii?neeo
eaeeioeoia. A oaoiieiaee eo i?iecaianoaa i?aaoniio?aiu nia-
oeaeuiua iaoiau oeie?aneie aaeiioaieiaoee, iieiinou? ene-
e??a?uea ?ene ia?aiina ae?onia eee a?oaeo iaoiaaiiuo aaai-
oia.
EO i?aanoaaeyao niaie eiiieaen oeoieeiia, o?anoao?ueo a
?aaoeyoee eeaoi?iuo yooaeoi?ia eiioieoaoa, iaoiayueony iia
eiio?ieai Th-eeioioeoia. A ninoaa i?aia?aoa aoiayo EOI-a,
EE-1, EE-6, EE-12, oaeoi? iae?ica iiooiee (OII), oaeoi?u ei-
aeaeoee iea?aoee iae?ioaaia e eaeeioeoia. ?EE i?aeoe?anee
ia niaa??eo a?oaeo iaaeaoi?ia, e?iia i?e?iaiuo EOI-a, i?e-
uaiiuo ai oaaeuiie aeoeaiinoe auoa 1 iei. ME ia 1 ia aaeea.
Eiioiiaeieiae?aneea yooaeou EO iaoneiaeaiu aai niinia-
iinou? noeioee?iaaou i?ieeoa?aoe?, aeooa?aioe?iaeo e ooie-
oeiiaeuio? aeoeaiinou oaeia?iuo noaiieyoee O-eeioioeoia
(i?aeiouanoaaiii Th). EO iiauoaao yeni?anne? aioeaaiia
aeaaiiai eiiieaena aenoiniaianoeiinoe 2-ai eeanna (AEA) e noe-
ioee?oao aaiiiiyc, iiaaaeaiiue oeoinoaoe?aneie oa?aieae (2).
Iia aaenoaeai EO a i?aaiecia iiooieaaiai aieuiiai aeoeae?o-
?ony ?aaeoee i?ioeaiiiooieaaiai eiioieoaoa. E?iia oiai, nie-
?aaony au?a?aiiinou yaeaiee eioieneeaoee, a oae?a oeoiiaiey
e eiioiiaai?anney, iaoneiaeaiiua eae iiooieaaui i?ioan-
nii, oae e aaenoaeai oeoinoaoe?aneiai ea?aiey. EO i?eiaiyee
ii iaiie aiioea aioo?aiuoa?ii 2-3 ?aca a iaaae?. E?aoiinou
aaaaaiey auea oai auoa, ?ai oy?aeaa eeeie?aneia ninoiyiea.
?EE a ioee?ea io ?aeiiaeiaioiuo EOI, yaey?ueony iiii-
i?aia?aoaie, niaa??eo eiiieaen i?e?iaiuo EOI (aieaa 10 ei-
aeaeaoaeuiuo eiiiiiaioia) e ia aucuaaao ia?aciaaiey aioeoae
i?e aeeoaeuiii i?eiaiaiee. Iaiaei a aica 1 iei. ME e aieaa
?EE ii?ao i?eaiaeou e iiaaaeaie? aaiiiiyca, iiyoiio aai ?a-
eiiaiaoaony eiiaeie?iaaou n EO. ?EE niiniaai iiaaaeyou
?ino e noeioee?iaaou oeoieec iiooieaauo eeaoie (1).
Aeeoaeuiua iaae?aaiey ca 246 aieuiuie ?I? II-IVA, ?? III-
IV noaaee, eioi?ua iieo?aee eiioiiei??aeoe?, iieacaee iani-
iiaiio? oaeaniia?aciinou aa aee??aiey a noaiu oa?aiee ia
anao yoaiao ea?aiey.
I?eiaiaiea EO ai a?aiy e iinea eo?nia eo?aaie oa?aiee no-
uanoaaiii (a 2-3 ?aca) nie?auaei n?iee iineaeo?aaie eiioii-
?aaaeeeoaoee. E?aeia aa?ii, ?oi EO iicaieye oaaee?eou eioai-
neaiinou e i?iaie?eoaeuiinou eo?aaie oa?aiee. EO auno?i ain-
noaiaaeeaae eiee?anoai e ooieoeiiaeuio? aeoeaiinou eiioi-
iuo yooaeoi?ia. A oy?aeuo neo?ayo ii?ii auei i?eiaiyou ii-
auoaiiua aicu IOO aac ia?ooaiey iauae noaiu oa?aiee eee
oaeeiaiey ia?eo?niauo eioa?aaeia.
I?eiaiaiea EO ia anao yoaiao ea?aiey ?I? IIIA noaaee (ia-
noiia iaeo?aiea, ianoyeoiiey e a eo?nia IOO ii noaia CMF)
i?aaioa?auaei ?acaeoea iaoanoacia e i?e 5-eaoiai iaae?aa-
iee i?eaaei e nie?aie? ?anoiou aaia?aeecaoee i?ioanna a 5
?ac (n 52% a a?oiia n?aaiaiey ai 10% a a?oiia n EO).
A neo?ayo, eiaaa aaia?aeecaoee ecaa?aou ia oaaeinu, a?aiy
iaia?o?aiey iaoanoacia ioiaaeioeinu n 13,2±1,4 ai 30,5±2,0
ian i?e iauai cia?eoaeuiii oeo?oaiee ea?anoaa ?ecie. Nie-
iaeanu eee nouanoaaiii nie?auaeanu au?a?aiiinou neiioi-
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