Auaiau.
Iieeoeieioa?aiey n eniieuciaaieai noaiu CMF
iicaieyao o 53% aieuiuo n aaeaei caoaaoeie noaaeyie ?aea
iiei?iie ?aeacu aiaeouny noaaeeecaoee eee ?anoe?iie ?aa?an-
nee iiooiee, oai naiui iaeaa?ay no?aaaiey ia?a?aiiuo aieu-
iuo.
III Eiia?ann «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey a ca?aaiio?a-
iaiee», ai?aeu 2000, Aioaeey, «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoa-
oey», 2000, ¹ 1-2, n. 72.
ÏÅÐÂÛÉ ÎÏÛÒ ËÅ×ÅÍÈß ÁÎËÜÍÛÕ
Ñ ÍÅÕÎÄÆÊÈÍÑÊÈÌÈ ËÈÌÔÎÌÀÌÈ
ÌÅÒÎÄÎÌ ÀÓÒÎÃÅÌÎÕÈÌÈÎÒÅÐÀÏÈÈ
?.N. Neai?aiei, E.A. Ae?aiaoia, A.E. Aa?oiaoaaa,
A.?. Ceaoiee, E.A. Ai?ioeineay, A.I. Iaiiiiyuay
Iao?ii-enneaaiaaoaeuneee einoeooo iieieiaee, ?inoia-ia-Aiio,
?inney
A ioaaeaiee oeieiai?iiiioa?aiee ?IEIE ea?aie? iiaaa?-
aaeenu 13 aieuiuo n iaoia?eeineeie eeioiiaie (IOE) a aic-
?anoa io 27 ai 70 eao. Ana aieuiua auee ia?ae?iuie n aa?eoe-
oe?iaaiiui aeaaiicii. Io??ei auei 8, ?aiuei — 5; II noaaey
aeaaiinoe?iaaia o 3 aieuiuo, III — o 8, IV — o 2; IOE aunieie
noaiaie ceiea?anoaaiiinoe auyaeaiu o 9 aieuiuo, ieceie — o 4.
Ea?aiea aieuiuo i?iaiaeee ii noaiai CHOP e CVPP. 8 aieu-
iui i?iaaee aooiaaiioeieioa?aie? (AAOO) (iniiaiay a?oiia),
5 aieuiui — noaiaa?oio? iieeoeieioa?aie? (eiio?ieuiay
a?oiia). A nayce n oai, ?oi iu ia eiaai ainoaoi?iuo n?ieia ia-
ae?aaiey ca aieuiuie, yooaeoeaiinou ea?aiey auea ioaiaia
ii iaiin?aanoaaiiui ?acoeuoaoai. A iniiaiie e eiio?ieuiie
a?oiiao ?anoe?iua ?aa?annee ainoeaioou o 5 e 4 aieuiuo, noaae-
eecaoey i?ioanna — o 3 e 1 niioaaonoaaiii. Oiene?iinou eaea?-
noaaiiiai ea?aiey a iaaeo a?oiiao ioaieaaee ii ?eneo i?iaa-
aaiiuo eo?nia (ii 12 a ea?aie a?oiia). Iniiaiuie oiene?anee-
ie i?iyaeaieyie auee eaeeiiaiey, aeniaioe?aneea neiioiiu
e aeiiaoey. A iniiaiie e eiio?ieuiie a?oiiao eaeeiiaiey
ano?a?aeanu a 2 (17%) eo?nao e 4 (33%) eo?nao, aeniaioe?aneea
neiioiiu — a 9 (75%) eo?nao e 6 (50%) eo?nao, aeiiaoey — a 6
(50%) eo?nao e 9 (75%) eo?nao niioaaonoaaiii. Oaeea inei?ia-
iey, eae ea?aei- e iao?ioiene?iinou auee iaiaa au?a?aiiu-
ie. O?eouaay ?acoeuoaou iiiaieaoiaai iiuoa i?eiaiaiey ia-
o?aaeoeiiiuo iaoiaia eaea?noaaiiie oa?aiee a ?IEIE e au-
oai?eaaaaiiua aaiiua, iaiaoiaeii ioiaoeou, ?oi iaoia AAOO,
iaeaaay eiioiiiiaoee?o?uei e iaia?aiinoaaeeece?o?uei
aaenoaeai, yaeyaony ooieoeiiaeuii-uaayuei, eaa?a ia?aii-
neony aieuiuie e nii?iai?aaaony iaiuoei ?eneii iiai?iuo
yooaeoia.
III Eiia?ann «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey a ca?aaiio?a-
iaiee», ai?aeu 2000, Aioaeey, «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoa-
oey», 2000, ¹ 1-2, n. 66.
ÏÅÐÑÏÅÊÒÈÂÛÌÅÒÎÄÀ
ÀÓÒÎÃÅÌÎÕÈÌÈÎÒÅÐÀÏÈÈ
 ÏÀËËÈÀÒÈÂÍÎÉ ÎÍÊÎËÎÃÈÈ
?.N. Neai?aiei, E.?. Aeaaeie?iaa, A.?. Ceaoiee,
A.E. Aa?oiaoaaa
Iao?ii-enneaaiaaoaeuneee einoeooo iieieiaee, ?inoia-ia-Aiio,
?inney
?ac?aaioaiiue a ?IEIE iaoia aooiaaiioeieioa?aiee
(AAOO) iicaieyao iiauneou yooaeoeaiinou ea?aiey i?e ?acee?-
iie iieieiae?aneie iaoieiaee, a oae?a nieceou iiai?iua yooa-
eou oeoinoaoeeia. Aai aaeuiaeoei niaa?oainoaiaaieai yae-
eanu ?ac?aaioea iaoiaeee aooieeaoi?iie eiioiiei??aeoee, i?e
eioi?ie eeaoee e?iae ia?aaaouaa?o i?aia?aoii, iaeaaa?uei
eiioiiiiaoee?o?ueie naienoaaie — iieeiaioeaiui yeno?ae-
oii yieoeca — yieoaeaieiii (Y). Iaoia AAOO n aooieeaoi?iie
eiioiiei??aeoeae (AAOO + Y) aue i?eiaiai o 20 aieuiuo ?a-
eii iiei?iie ?aeacu III-IV noaaee (O2-4N1-2I0-1, aaa I1 — ia-
oanoacu a iaaee??e?iuo eeioaoe?aneeo oceao ia noi?iia ii?a-
?aiey) a aic?anoa io 35 ai 70 eao, ia?ae?iuo, n oeoieiae?aneie
aa?eoeeaoeae aeaaiica, iiaaa?aoeony iaiaau?aaioiiio ea?a-
ie? ii noaiai CMFV e CMAV. Aaaaaiea Y inouanoaeyeinu ii
10 ia/noo a?aaiaaii ia i?ioy?aiee anaai eo?na. Eiio?ieuiua
a?oiiu auee niiinoaaeiu ii iniiaiui i?eciaeai e ninoiyee ec
aieuiuo, iiaaa?aoeony AAOO e nenoaiiie oeieioa?aiee (NOO)
aac aooieeaoi?iie eiioiiei??aeoee. Ia?yao n eiioiieiae?an-
eeie iieacaoaeyie ioaieaaee yooaeoeaiinou ea?aiey e iiai?-
iua oiene?aneea yooaeou oeoinoaoeeia ii e?eoa?eyi AIC. Iae-
aieuoay yooaeoeaiinou ioia?aia a a?oiia AAOO+Y (iieiua e
?anoe?iua ?aa?annee — 83%), ?oi nii?iai?aaeinu cia?eoaeuii
iaiuoeie iieacaoaeyie ?anoiou e au?a?aiiinoe oiene?iinoe
ii n?aaiaie? n aiaeiae?iuie iieacaoaeyie a iaaeo eiio?ieu-
iuo a?oiiao. I?e aiaeeca aaiiuo eiioiieiae?aneiai enneaai-
aaiey onoaiiaeaii, ?oi NOO iaeaaaea ?aceei eiioiiaai?an-
neaiui yooaeoii n oaiaoaieai ooieoeiiaeuiie aeoeaiinoe O- e
A-eeioioeoia, a oae?a ii eo eiee?anoaaiiui iieacaoaeyi noa-
iiioeyoee, ?aai ia iaae?aaeinu i?e AAOO. Iaoia AAOO+Y iic-
aieee ainoiaa?ii oaaee?eou ooieoeiiaeuio? aeoeaiinou O-eea-
oie, a oae?a iiauneou eiioii?aaoeyoi?iue eiaaen. Oaeei ia?a-
cii, o?eouaay cia?eiinou a iaeeeaoeaiie iieieiaee uaayueo
iaoiaia ea?aiey, eeeieei-eiioiieiae?aneea oa?aeoa?enoeee
AAOO e aicii?iinou i?eiaiaiey aooieeaoi?iie eiioiiei??ae-
oee, iicaiey?o aiai?eou i iiauo ia?niaeoeaao ea?aiey aieuiuo
n aunieie noaiaiu? ?ani?ino?aiaiiinoe iieieiae?aneeo caai-
eaaaiee.
III Eiia?ann «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey a ca?aaiio?a-
iaiee», ai?aeu 2000, Aioaeey, «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoa-
oey», 2000, ¹ 1-2, n. 58.
ÁÈÎÒÅÐÀÏÈß ÍÀ ÎÑÍÎÂÅ ËÈÌÔÛ
 ËÅ×ÅÍÈÈ ÁÎËÜÍÛÕ
ÐÀÑÏÐÎÑÒÐÀÍÅÍÍÛÌ ÐÀÊÎÌ ßÈ×ÍÈÊÎÂ
?.N. Neai?aiei, E.?. Aieioeia, A.A. Ia?iai, A.?. Ceaoiee,
O.A. ?aeaaiaa, E.A. Ae?aiaoia
Iao?ii-enneaaiaaoaeuneee einoeooo iieieiaee, ?inoia-ia-Aiio,
?inney
?ae ye?ieeia (??) caieiaao o?aoua ianoi n?aae iieiaeiaei-
eiae?aneie iaoieiaee, ii aianoa n oai yaeyaony iniiaiie i?e?e-
iie nia?oe ?aiuei, no?aaa?ueo ?aeii iieiauo i?aaiia, e ca-
ieiaao ?aoaa?oia ianoi a no?oeoo?a iauae nia?oiinoe io ceiea-
?anoaaiiuo iiaiia?aciaaiee. O 65-79% iaoeaioie aeaaiic ??
onoaiaaeeaa?o a III-IV noaaee caaieaaaiey. Ianiio?y ia aeoea-
iia i?eiaiaiea oe?o?ae?aneiai, eo?aaiai e eaea?noaaiiiai ia-
oiaia a ea?aiee ??, 5-eaoiyy au?eaaaiinou aieuiuo i?e anao
noaaeyo caaieaaaiey eieaaeaony a i?aaaeao 25-35%. Yooaeoea-
iinou oeacaiiuo iaoiaia ea?aiey inoaaony iaoaiaeaoai?eoaeu-
iie. A nayce n yoei oaeu? iaoae ?aaiou yaeeinu iiauoaiea ?a-
caeoaaaeuiinoe ?ani?ino?aiaiiuo oi?i ?aea ye?ieeia (??) n
iiiiuu? iaiaau?aaioiie aeioa?aiee ia iniiaa eeiou — ia-
oiaa, eioi?ue i?aanoaaeyao niaie aiaeia aaaioeaiie eiioiioa-
?aiee, O 22 aieuiuo ?? IV noaaee n eiaaenii Ea?iianeiai ie?a
60 aaeeia a aic?anoa io 43 ai 68 eao i?iaaaaia iaiaau?aaioiay
aooi- (19 aieuiuo) e aiii- (3 aieuiuo) eeioioeieioa?aiey ii
noaiai CMF, CAF e CAP a eioaineaiuo ?a?eiao. Aeea?ae?aneeo
e au?a?aiiuo iauaoiene?aneeo ?aaeoee ia ioia?aii ie a ia-
iii neo?aa. Iauaeoeaiue yooaeo, iiaoaa??aaiiue aaiiuie
oeuo?aniiia?aoe?aneiai enneaaiaaiey, iieo?ai o anao aieuiuo:
?anoe?iay ?aienney — o 15, noaaeeecaoey — o 7. O 20 aieuiuo a
iineaao?uai auiieiaia iia?aoey a iieiii iauaia, ?acia?
?aceaoaeuiie iiooiee — iaiaa 2 ni, o 2 aieuiuo — oeoi?aaoe-
545
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