15. Joueux H., Szawlowski A. W., Saint-Aubert B. et al. Progres-
sive regional surgery for advanced ovarian carcinoma.// Can-
cer. — 1986. — 57(1). — 132—147.
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phamide and Cisplatin in patients with stage III and stage IV
ovarian cancer.// NEJM. — 1996. — 334. — 1—6.
17. Neit J. P. The place combination chemotherapy in the treat-
ment of advanced ovarian Cancer the way a head. //Ed. F.
Sharp, W. P. Soutter. — 1987. — 329—342.
18. Omura G., Erlich C. E., Blessing J. A. et al. A randomized trial
of cyclophosphamide plus adriamycine with or without cis-
platin in ovarian carcinoma.// Proc. Am. Soc. Clin. Oncol. —
1982. — 1. — 109.
19. Paclitaxel (PX)-carboplatin (CBP) versus cyclophoshamide
(ctx) — carboplatin supported by G-CSF as first line
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pean Cancer Conference Hamburg. — 14—18 September
1997. — abstr. 545.
20. Piccart M. J., Gore M., Ten Bokkel Huinink W. et al. Doc-
etaxel: an active new drug for treatment of advanced epithelial
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676—681.
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my.// Gynecol. Oncol. — 1988. — 31 (8). — 3—21.
22. Vermorken J. B., Hoekman K. Chemotherapy for gynecologic
malignancies.// Current. Opin. Oncol. —1995. —7. —457—465.
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1994. — 5. — 495—506.
24. Walker H., Stuart G., Bacon M. Comparative cost-effective-
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Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey, 2001, ¹ 1, n. 40-45.
ÏÀËËÈÀÒÈÂÍÎÅ ÂÎÇÄÅÉÑÒÂÈÅ
ÏÐÈ ÐÀÊÅ ÌÎËÎ×ÍÎÉ ÆÅËÅÇÛ
I.A. Aa?aiiaa, A.E. Aa?oiaoaaa, I.A. Ieeieaaaa
?inoianeee iao?ii-enneaaiaaoaeuneee einoeooo iieieiaee,
?inoia-ia-Aiio, ?inney
Io 40 ai 70% neo?aaa ?aea iiei?iie ?aeacu (?I?) aia?aua
auyaey?ony ia noaaee ianoii-?ani?ino?aiaiiiai eee aaia?aee-
ciaaiiiai i?ioanna, eioi?ue ?anoi nii?iai?aaaony oaeeie
neiioiiaie, eae aieu, ioae, eaioa?iiaoiciua ycau, e?iaioa?a-
iea e a?.
N oaeu? oeo?oaiey ninoiyiey aaiiie a?oiiu aieuiuo a ?in-
oianeii IEE iieieiaee aue ?ac?aaioai i?eaeiaeuiue iaoia
ianoii-?aaeiia?iiai eaea?noaaiiiai aicaaenoaey i?e ?I?. Ii
i?aaoniao?eaaao aaaaaiea ia?aooii?aeuii aeeeioaiaea, ia-
euo aic iaoio?aenaoa e iiaiai i?aia?aoa ec a?oiiu ianoiuo
aianoaoeeia, o eioi?iai iaia?o?aiu aaeoa?einoaoe?aneia e ei-
ioiiiiaoee?o?uaa naienoaa.
Iaae?aaee 32 ia?ae?iuo aieuiuo ?I? a aic?anoa 27-69 eao
(n?aaiee aic?ano 52 aiaa) ni noaiaiu? ?ani?ino?aiaiiinoe
T4N1-2MO-1. O 5 iaoeaioie auea auyaeaia oceiaay oi?ia ?I?,
o 2 — ioa?ii-eioeeuo?aoeaiay, o inoaeuiuo — oceiaay ni aoi?e-
?iui ioaeii. Iinea 3-7 aaaaaiee o anao aieuiuo oeo?oeeinu
naii?oanoaea, en?acee aiee a iaeanoe iiei?iie ?aeacu (21 ec
21), i?e?ai o 5 iinea ia?aiai aaaaaiey ioia?aiu oiaiuoaiea
eioeeuo?aoee iyaeeo oeaiae ca i?aaaeaie ?aeacu (7 ec 7), i?e-
uaiea e ?anoe?iay yieoaeecaoey yca (9 ec 9). O aieuoeinoaa ia-
oeaioie iaae?aaeinu oiaiuoaiea ioaea ?aeacu (25 ec 27). A 3
neo?ayo caoeene?iaaii oiaiuoaiea ?acia?a ia?ae?iie iiooi-
ee e iaoanoaoe?aneeo eeioaoe?aneeo oceia.
Oaeei ia?acii, ianoii-?aaeiia?iia eaea?noaaiiia aicaaeno-
aea iicaieyao noauaeoeaii e iauaeoeaii oeo?oeou ninoiyiea
aieuiuo i?e ?I? e ii?ao auou i?eiaiaii eae naiinoiyoaeuiia
a ea?anoaa iaeeeaoeaiiai o iaoeaioie, eioi?ui ia iieacaii nia-
oeaeuiia ea?aiea, eee i?e ioeaca io oaeiaiai, eeai eae aiiieia-
iea e o?aaeoeiiiui oa?aiaaoe?aneei iaoiaai ea?aiey ?I?.
V Eiioa?aioey «Iaeeeaoeaiay iiiiuu a iieieiaee», ai?aeu, 2001,
Aia?oi, Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey, 2001, ¹ 2-3, n. 39.
ÈÑÏÎËÜÇÎÂÀÍÈÅ ÀÍÒÈÎKÑÈÄÀÍÒÎÂ
 KÎÌÏËÅKÑÍÎÌ ËÅ×ÅÍÈÈ ÁÎËÜÍÛÕ
ÐÀKÎÌÌÎËÎ×ÍÎÉ ÆÅËÅÇÛ
A.A. Aeyniaa, K.I. Kiioi?ueeiaa, E.A. Oa?aiouaa
IAIA, I. Iiaai?ia, ?inney
Oaeu enneaaiaaiey:
ioaieou aicii?iinoe eniieuciaaiey
aeieiae?anee aeoeaiie aiaaaee aeineai N (per. oainoiaa?aiea
Ieica?aaa ?O ¹000141.?.643.08.98), nicaaiiie ia iniiaa aei-
oeaaaiieaia e iaeaaa?uae iiuiui aioeieneaaioiui aaeno-
aeai a eiiieaeniii ea?aiee aieuiuo ?aeii iiei?iie ?aeacu.
Iaoa?eae e iaoiau.
Iia iaae?aaieai iaoiaeeenu 30 ?ai-
uei a aic?anoa 40-65 eao n aenoieiae?anee iiaoaa??aaiiui ae-
aaiicii ?aea iiei?iie ?aeacu. Ia ia?aii yoaia ea?aiey ana
aieuiua i?ioee eo?aao? oa?aie?, caoai oe?o?ae?aneia ea?a-
iea a iauaia ianoyeoiiee. 15 aieuiuo iieo?aee Aeineai N ia-
iia?aiaiii n ia?aui aau?aaioiui eo?nii oeoinoaoe?aneie oa-
?aiee. Inoaeuiui iaoeaioeai i?iaiaeeanu noaiaa?oiay iieeoe-
ieioa?aiey. A?oiiu auee niiinoaaeiu ii aic?anoo, noaaee caai-
eaaaiey, niioonoao?uae iaoieiaee. K?iia iauai?eiyouo eeeie-
?aneeo iaoiaia enneaaiaaiey o anao aieuiuo ioaieaaee ninoiy-
iea ia?aeeniiai ieeneaiey eeieaia e aioeieneaaioiie aeoeaii-
noe ieaciu e?iae, a oae?a ninoiyiea eiioiiiai noaoona n i?e-
iaiaieai iiiieeiiaeuiuo aioeoae.
?acoeuoaou.
A a?oiia aieuiuo, iieo?aaoeo Aeineai N iaii-
a?aiaiii n iieeoeieioa?aieae ioia?aeinu nie?aiea ?anoiou e
au?a?aiiinoe iiai?iuo yooaeoia oeoinoaoe?aneeo i?aia?aoia.
?a?a aicieeaee oioiioa e ?aioa, iauay neaainou, ii?iaeeci-
aaeny nii, ia iaae?aaeinu ?acaeoey eaeeiiaiee. Ii aaiiui
aeioaiee?ieianoaioee ioia?aeinu oaaee?aiea aioeieneaaio-
iie aeoeaiinoe ieaciu e?iae. A eiioiieiae?aneii noaoona eia-
eanu oaiaaioey e oaaee?aie? ?enea CD4
+
eeaoie e iiauoaie?
eiioii?aaoeyoi?iiai eiaaena.
A eiio?ieuiie a?oiia i?iaaaaiea oeoinoaoe?aneie oa?aiee
nii?iai?aaeinu au?a?aiiie oiene?iinou?. Iaiia?aiaiii
nie?aeanu aioeieneaaioiay aeoeaiinou ieaciu e iieacaoaee ei-
ioiiiai noaoona.
Oaeei ia?acii, i?eiaiaiea aeieiae?anee aeoeaiie aiaaaee
Aeineai N iicaieyao iiauneou ea?anoai ?ecie aieuiuo ?aeii
iiei?iie ?aeacu a i?ioanna eo eiiaeie?iaaiiiai ea?aiey.
V Eiioa?aioey «Iaeeeaoeaiay iiiiuu a iieieiaee», ai?aeu, 2001, Ai-
a?oi, Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey, 2001, ¹ 2-3, n. 68-69.
ÐÅÇÓËÜÒÀÒÛ ÓËÜÒÐÀÇÂÓÊÎÂÎÉ
ÄÎÏÏËÅÐÎÃÐÀÔÈÈ Â ÎÖÅÍÊÅ
ÍÅÎÀÄÚÞÂÀÍÒÍÎÉ ÏÎËÈÕÈÌÈÎÒÅÐÀÏÈÈ
I.A. A?caianoaaa, I.A. Noa??aoeay
?inoianeee iao?ii-enneaaiaaoaeuneee iieieiae?aneee einoeooo,
?inoia-ia-Aiio, ?inney
Oaeu enneaaiaaiey:
eco?aiea ?acoeuoaoia oeuo?acaoeiaie
aiiiea?ia?aoee aey ioaiee iaiaau?aaioiie oeieioa?aiee ia-
noii-?ani?ino?aiaiiiai ?aea iiei?iie ?aeacu.
555
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