oeaiay iia?aoey a iauaia aaonoi?iiiae aaiaenyeoiiee. Oaeei
ia?acii, iaoia aeioa?aiee ia iniiaa aooi- e aiiieeiou o in-
eaaeaiiuo aieuiuo ?ani?ino?aiaiiui ?? iicaieyao a ei?ioeea
n?iee i?iaiaeou aicieioaineaiua eo?nu iaiaau?aaioiie oe-
ieioa?aiee e ia?aaiaeou aieuiuo a iia?aaaeuiia ninoiyiea.
Ia iniiaaiee iieo?aiiuo aaiiuo ii?ii n?eoaou, ?oi iaoia ao-
oi- e aiiieeioioeieioa?aiee, ni?aoay a naaa oaeea iaoaieciu
ea?aaiiai aicaaenoaey, eae eiioiiiiaoeyoey, aaceioieneea-
oey, iioeiecaoey oa?iaeieeiaoe?aneeo e oa?iaeiaeiaie?an-
eeo naienoa oeieii?aia?aoia, iiauoaiea yooaeoeaiinoe aa?a-
niie ainoaaee oeieii?aia?aoia, i?aanoaaeyao niaie ia?niae-
oeaiue eiiieaeniue aeioa?aiaaoe?aneee iaoia aicaaenoaey ia
ceiea?anoaaiiue ?ino.
III Eiia?ann «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey a ca?aaiio?a-
iaiee», ai?aeu 2000, Aioaeey, «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoa-
oey», 2000, ¹ 1-2, n. 65.
ÈÌÌÓÍÎËÎÃÈ×ÅÑÊÈÅ È ÁÈÎÕÈÌÈ×ÅÑÊÈÅ
ÊÐÈÒÅÐÈÈ ÎÁÎÑÍÎÂÀÍÍÎÑÒÈ
ÏÐÈÌÅÍÅÍÈß ËÈÌÔÎÕÈÌÈÎÒÅÐÀÏÈÈ
Ó ÁÎËÜÍÛÕ ÐÀÑÏÐÎÑÒÐÀÍÅÍÍÛÌ
ÐÀÊÎÌ ßÈ×ÍÈÊÎÂ
?.N. Neai?aiei, E.?. Aieioeia, A.A. Ia?iai, A.?. Ceaoiee,
A.E. Caei?a, E.A. Ai?ioeineay, E.A. Ae?aiaoia, A.E. Ai?ei,
O.A. ?aeaaiaa
Iao?ii-enneaaiaaoaeuneee einoeooo iieieiaee, ?inoia-ia-Aiio,
?inney
A ?IEIE ?ac?aaioai i?eaeiaeuiue eiiieaeniue aeioa?a-
iaaoe?aneee niinia aicaaenoaey ia iiooieu — aooieeioioeiei-
oa?aiey (AEOO). A yenia?eiaioa e eeeieea aieacaiu ianiiiai-
iay yooaeoeaiinou e oaeaniia?aciinou i?eiaiaiey AEOO a ea-
?aiee aieuiuo ni ceiea?anoaaiiuie iiooieyie ?acee?iuo eiea-
eecaoee, a oii ?enea aieuiuo ?aeii ye?ieeia. A iaoae ?aaioa
eco?aii aeeyiea i?aaiia?aoeiiiie aooieeioioeieioa?aiee o
12 i?aeoe?anee eieo?aaaeuiuo aieuiuo ?ani?ino?aiaiiui ?a-
eii ye?ieeia (??) ia aeiaieeo eiioiieiae?aneeo iieacaoaeae
e?iae e ninoiyiea eeaoi?iuo iaia?ai eeioioeoia (EO) e y?eo-
?ioeoia (Y?) e?iae ai e iinea ea?aiey. A aeiaieea AEOO ia oi-
ia iacia?eoaeuiiai nie?aiey AI-?IE (A-EO) a ?aaeoee niii-
oaiiiai ?icaoeiia?aciaaiey ioia?aaony noaoenoe?anee ainoi-
aa?iia oaaee?aiea ooieoeiiaeuiie aeoeaiinoe O-EO a ?aaeoee
aeanoo?ainoi?iaoee ia O-ieoiaaiu. O aieuiuo n aunieei eee-
ie?aneei yooaeoii a aeiaieea AEOO auei iaia?o?aii oaaee-
?aiea niaa??aiey CD4
+
e CD16
+
eeioioeoia, ?oi, ianiiiaiii,
yaeyaony iiceoeaiui yooaeoii. Iiceoeaiay aeiaieea eiioii-
eiae?aneeo iieacaoaeae a cia?eoaeuiie noaiaie ii?aaaeyaony
ninoiyieai iaia?ai eeaoie e?iae, aeaaiui ia?acii iieacaoa-
eai iaia?aiiie oaeo?anoe. Iinea AEOO ioia?aii oaaee?aiea
ai o?iaiy aiii?ia oaeo?anoe iaia?ai EO e Y? a ciia aaeie-ee-
ieaiuo eiioaeoia e eeieaiiai aeneiy, ecia?aeuii nie?aiiie o
aieuiuo ia 24-31 e 39-43% niioaaonoaaiii, e nie?aiea niaa?-
?aiey aiay?eo?ioeoa?iiai aaiiaeiaeia, oaaee?aiea eioi?iai a
1,5 ?aca o aieuiuo ai ea?aiey io?a?aei iiauoaiea i?iieoaa-
iinoe iaia?ai eeaoie e?iae. Iieo?aiiua aaiiua naeaaoaeuno-
ao?o i oii, ?oi AEOO ia i?eaiaeo e oaiaoaie? eiioiiiai noaoo-
na aieuiuo ?ani?ino?aiaiiui ?? e nii?iai?aaaony ii?iaee-
caoeae oaeo?anoe e i?iieoaaiinoe iaia?ai eeaoie e?iae. Ia-
ae?aaaiue i?e yoii oi?ioee eeeie?aneee yooaeo ea?aiey iic-
aieyao ?aeiiaiaiaaou iaoia AEOO e aieaa oe?ieiio i?eiaia-
ie? o aieuiuo ?aeii ye?ieeia a ea?anoaa iaiaau?aaioiie oe-
ieioa?aiee.
III Eiia?ann «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey a ca?aaiio?a-
iaiee», ai?aeu 2000, Aioaeey, «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoa-
oey», 2000, ¹ 1-2, n. 65-66.
ÍÅÎÀÄÚÞÂÀÍÒÍÀß ÕÈÌÈÎÒÅÐÀÏÈß
ÐÀÊÀ ÆÅËÓÄÊÀ
A.E. Nieiauaa, I.?. Oaooei, O.A. Aia?aaaa
Iaeanoiie iieieiae?aneee eeeie?aneee aeniaina?, Niieaine,
?inney
A?aaiaii a Niieaineie iaeanoe ?aaeno?e?o?ony io 450 ai
490 aieuiuo ?aeii ?aeoaea. Iaeanou yaeyaony yiaaie?iie ii
?aeo ?aeoaea. Caaieaaaaiinou ninoaaeyao 42 ia 100000 ianaea-
iey (?O — 35 ia 100000 ianaeaiey). Au?eaaaiinou i?e ?aea ?a-
eoaea inoaaony iaoaiaeaoai?eoaeuiie e iniaiai i?ia?anna a ea-
?aiee yoiai a?iciiai caaieaaaiey ia iieo?aii.
Yooaeoeaiinou oeoinoaoeeia, i?eiaiyaiuo a ea?aiee ?aea
?aeoaea, ii ioaaeuiinoe ia i?aauoaao 30%. Kiiaeiaoee oeoi-
noaoeeia iiauneee yooaeoeaiinou ea?aiey ?aea ?aeoaea ai 36%
e noaee i?eiaiyouny i?e ea?aiee aaia?aeeciaaiiuo oi?i ?aea
?aeoaea. Iaiaei ?acoeuoaou ea?aiey aaia?aeeciaaiiiai ?aea
inoa?ony iea?aaiuie e i?aeoe?anee ia oeo?oeeenu. A ianoiy-
uaa a?aiy a aieuoeinoaa eeeiee ie?a i?eiaiy?ony iineaiia-
?aoeiiiua eo?nu oeieioa?aiee i?e ?aea ?aeoaea IIIA noaaee,
oioy ai neo ii? aii?in i oaeaniia?aciinoe i?iaaaaiey iinea-
iia?aoeiiiie oeieioa?aiee iinea ?aaeeaeuiuo iia?aoee, inoa-
aony ioe?uoui.
N 1997 a. a iaoai aeniaina?a ia?aee i?eiaiyou iaiaau?-
aaioio? oeieioa?aie? ii noaia AA? o aieuiuo ?aeii ?aeoa-
ea. Iu aua?aee i?iaiinoe?anee iaaeaaii?eyoiua oi?iu ?aea
?aeoaea: iaaeooa?aioe?iaaiiue eee ia?noiaaeaii-eeaoi?iue
?ae, ia?ae?ii-ycaaiii-eioeeuo?aoeaiay oi?ia ?inoa o aieu-
iuo iieiaiai aic?anoa. Ia?ae?iue ycaaiii-eioeeuo?aoeaiue
?ae ?aeoaea iaei eco?ai eae eeeieoenoaie, oae e iaoiaenoiei-
aaie. A ianoiyuaa a?aiy ia?ae?iue ycaaiii-eioeeuo?aoeaiue
?ae ia?ae ano?a?aouny ana ?aua, oa?aiea aai ao?iia, auno?i
aaao iaoanoacu e i?eaiaeo e aaia?aeecaoee ?aeiaiai i?ioan-
na. Enoiay ec e?eoa?eaa auai?a iaoiaa ea?aiey, aaoaio aie-
iaie? iu ii?ai i?aanoaaeou iaiiaiae?io? eaoaeuiinou o
a?oiiu aieuiuo ?aeii ?aeoaea ec 14 ?aeiaae. Aieuiui i?iaa-
aaii 2 eo?na iaiaau?aaioiie oeieioa?aiee ii noaia AA? n
eioa?aaeii 28 aiae n iineaao?uei iia?aoeaiui aiaoaoaeu-
noaii a iauaia eiiaeie?iaaiiie aano?yeoiiee n eeioiae-
nnaeoeae R2. O 6 aieuiuo ioia?aia eaea?noaaiiue iaoaii?oic
I noaiaie (42,8%), II noaiaiu auyaeaia o 6 (42,8%) aieuiuo; o
aaoo aieuiuo ioia?aeanu I noaiaiu eaea?noaaiiiai iaoaii?oi-
ca (14,2%). Aieuiuo n ionoonoaeai yooaeoa io oeieioa?aiee,
ia auei. 11 (78,57%) ?aeiaae ec 14 ia?a?eee iaei aia iinea
i?iaaaaiiiai eiiaeie?iaaiiiai ea?aiey aac i?eciaeia ?aoe-
aeaa e i?ia?anna caaieaaaiey. Iaiiaiae?iay eaoaeuiinou ni-
noaaeea 21,43%.
Oaeu niiauaiey:
o aieuiuo n iaeaieaa ceiea?anoaaiiui oa-
?aieai ?aea ?aeoaea i?eiaiyeanu iaiaau?aaioiay oeieioa?a-
iey, eioi?ay iaei eco?aia.
Auaia:
Kiiaeie?iaaiiia ea?aiea n i?eiaiaieai iaiaau?-
aaioiie oeieioa?aiee o aieuiuo n ia?ae?iui ycaaiii-eioeeuo-
?aoeaiui ?aeii ?aeoaea ia oooaoeei iaiiaiae?io? au?eaaa-
iinou. N?eoaai oaeaniia?aciui i?iaie?eou i?eiaiaiea ia-
iaau?aaioiie oeieioa?aiee i?e iaeaieaa iaaeaaii?eyoiuo
oi?iao ?aea ?aeoaea.
III Eiia?ann «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoaoey a ca?aaiio?a-
iaiee», ai?aeu 2000, Aioaeey, «Iaeeeaoeaiay iaaeoeia e ?aaaeeeoa-
oey», 2000, ¹ 1-2, n. 77.
ÎÏÛÒ ÏÐÅÏÀÐÀÒÀ ÏÅÏÈÄÎËÏÝÃ Â ÊÎÐÐÅÊÖÈÈ
ÎÑËÎÆÍÅÍÈÉ ÕÈÌÈÎÒÅÐÀÏÈÈ
N.A. No?a?aa, Y.A. Iioeaaneee
Iineee iaeanoiie iieieiae?aneee aeniaina?, Iine, ?inney
Eniieuciaaiea a ea?aiee iieieiae?aneeo aieuiuo i?ioeai-
iiooieaauo eaea?noaaiiuo n?aanoa ?anoi nii?iai?aaaony iiai-
546
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